Cetuximab



Erbitux™







Cetuximab

(se TUK see mab)

U.S. Brand Names
Erbitux™
Pharmacologic Category
Antineoplastic Agent, Monoclonal Antibody; Epidermal Growth Factor Receptor (EGFR) Inhibitor
What key warnings should I know about before taking this medicine?
  • Some patients experience severe reactions during the infusion.
Reasons not to take this medicine
  • If you have an allergy to cetuximab or any other part of this medicine.
  • If you are allergic to mouse proteins, talk with healthcare provider.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
  • If you are pregnant or may be pregnant.
  • If you are breast-feeding.
What is this medicine used for?
  • This medicine is used to treat colorectal cancer.
  • This medicine is used to treat head and neck cancer.
How does it work?
  • Cetuximab injures cancer cells causing their death.
How is it best taken?
  • Use prescription as directed, even if feeling better.
  • This medicine is given as a shot into a vein.
What do I do if I miss a dose? (does not apply to patients in the hospital)
  • Call healthcare provider for instructions.
What are the precautions when taking this medicine?
  • If you are 65 or older, use this medicine with caution. You could have more side effects.
  • If you have heart disease, talk with healthcare provider.
  • Tell dentists, surgeons, and other healthcare providers that you use this medicine.
  • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
  • You can get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen; wear protective clothing and eyewear.
  • Use birth control that you can trust to prevent pregnancy while taking this medicine.
What are some possible side effects of this medicine?
  • Flu-like symptoms. These include headache, weakness, fever, shakes, aches, pains, and sweating. Mild pain medicine may help.
  • Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.
  • Headache.
  • Diarrhea.
  • Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.
What should I monitor?
  • Change in condition being treated. Is it better, worse, or about the same?
  • Check blood work regularly. Talk with healthcare provider.
  • Follow up with healthcare provider.
Reasons to call healthcare provider immediately
  • If you suspect an overdose, call your local poison control center immediately or dial 911.
  • Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
  • Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.
  • Chest pain or pressure or fast heartbeat.
  • Severe dizziness or passing out.
  • Severe headache.
  • Severe nausea or vomiting.
  • Severe diarrhea.
  • Unusual bruising or bleeding.
  • Any rash.
  • No improvement in condition or feeling worse.
How should I store this medicine?
  • This medicine will be given to you in a healthcare setting. You will not store it at home.
General statements
  • If you have a life-threatening allergy, wear allergy identification at all times.
  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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