Zolmitriptan



Zomig®; Zomig-ZMT™







Zolmitriptan

(zohl mi TRIP tan)

U.S. Brand Names
Zomig®; Zomig-ZMT™
Canadian Brand Names
Zomig®; Zomig® Nasal Spray; Zomig® Rapimelt
Mexican Brand Names
Zomig®
Pharmacologic Category
Serotonin 5-HT
Reasons not to take this medicine
  • If you have an allergy to zolmitriptan or any other part of this medicine.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
  • If you have any of the following conditions: Certain types of migraines, chest pain or pressure, heart disease, uncontrolled high blood pressure, or Wolff-Parkinson-White syndrome.
  • If you have taken isocarboxazid, phenelzine, or tranylcypromine in the last 14 days. Monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine) must be stopped 14 days before this medicine is started. Taking the two together could cause dangerously high blood pressure.
  • If you have taken almotriptan, frovatriptan, naratriptan, rizatriptan, or sumatriptan in the last 24 hours.
  • If you have taken ergotamine, methysergide, or dihydroergotamine in the last 24 hours.
  • If you are pregnant or may be pregnant.
What is this medicine used for?
  • This medicine is used to treat headaches.
How does it work?
  • Zolmitriptan squeezes certain blood vessels in the brain preventing irritation and inflammation.
How is it best taken?
  • Oral:
  • You may break the tablet in half. Do not chew or crush.
  • Take this medicine with liquids as early as possible after the attack has started.
  • Oral-disintegrating tablet: Place on tongue and let dissolve. Water is not needed. Do not swallow whole. Do not chew, break, or crush.
  • Intranasal:
  • For the nose only.
  • Blow your nose before use.
  • Spray a single dose in one nostril as early as possible after the attack has started.
  • If the headache returns, the dose may be repeated once after 2 hours.
What do I do if I miss a dose? (does not apply to patients in the hospital)
  • This medicine is taken on an as needed basis.
What are the precautions when taking this medicine?
  • This medicine is not used to prevent future attacks.
  • Use caution if you have risk factors for heart disease (high blood pressure, high cholesterol, overweight, diabetes, cigarette smoking, male older than 40 years of age, other family members with early heart disease, postmenopausal female). Talk with healthcare provider.
  • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
  • You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.
  • Avoid alcohol (includes wine, beer, and liquor).
  • Use birth control that you can trust to prevent pregnancy while taking this medicine.
  • Tell healthcare provider if you are breast-feeding.
What are some possible side effects of this medicine?
  • Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.
  • Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.
  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
  • Dry mouth.
What should I monitor?
  • Change in condition being treated. Is it better, worse, or about the same?
  • Keep a diary of your headaches.
  • Dry mouth may cause an increase in cavities. Take good care of your teeth. See a dentist regularly.
Reasons to call healthcare provider immediately
  • If you suspect an overdose, call your local poison control center immediately or dial 911.
  • Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
  • No relief of headache after treatment.
  • Chest pain or pressure or fast heartbeat.
  • Severe belly pain or bloody diarrhea.
  • Severe dizziness or passing out.
  • Seizure.
  • Difficulty breathing.
  • Feeling extremely tired or weak.
  • Any rash.
  • No improvement in condition or feeling worse.
How should I store this medicine?
  • Store at room temperature.
  • Protect from light.
  • Protect from moisture. Do not store in a bathroom or kitchen.
  • Use Zomig-ZMT™ tablets right after opening.
General statements
  • If you have a life-threatening allergy, wear allergy identification at all times.
  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
Brand Names: