Lubiprostone
Amitiza™
Lubiprostone
(loo bi PROS tone)U.S. Brand Names
Amitiza™Pharmacologic Category
Gastrointestinal Agent, MiscellaneousReasons not to take this medicine
- If you have an allergy to lubiprostone or any other part of this medicine.
- Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
- If you have an intestinal blockage.
What is this medicine used for?
- This medicine is used to treat constipation.
How does it work?
- Lubiprostone softens the stool by increasing its water content.
How is it best taken?
- Take this medicine with food to prevent stomach upset.
What do I do if I miss a dose? (does not apply to patients in the hospital)
- Take a missed dose as soon as possible.
- If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
- Do not take a double dose or extra doses.
What are the precautions when taking this medicine?
- Check medicines with healthcare provider. This medicine may not mix well with other medicines.
- Tell healthcare provider if you are pregnant or plan on getting pregnant.
- Tell healthcare provider if you are breast-feeding.
What are some possible side effects of this medicine?
- Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
- Headache.
- Belly pain or heartburn.
- Diarrhea.
- Swelling.
What should I monitor?
- Change in condition being treated. Is it better, worse, or about the same?
- Take good care of your teeth. See a dentist regularly.
- Follow up with healthcare provider.
Reasons to call healthcare provider immediately
- If you suspect an overdose, call your local poison control center immediately or dial 911.
- Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
- Severe nausea or vomiting.
- Severe diarrhea.
- Any rash.
- No improvement in condition or feeling worse.
How should I store this medicine?
- Store capsules at room temperature.
- Protect from moisture. Do not store in a bathroom or kitchen.
General statements
- If you have a life-threatening allergy, wear allergy identification at all times.
- Do not share your medicine with others and do not take anyone else's medicine.
- Keep all medicine out of the reach of children and pets.
- Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
- Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
Brand Names:
Other drugs
- Labetalol
- Lactulose
- Lamivudine
- Lamotrigine
- Lansoprazole
- Lansoprazole and Naproxen
- Lansoprazole, Amoxicillin, and Clarithromycin
- Lanthanum
- Laronidase
- Latanoprost
- Leflunomide
- Lemon Balm
- Lenalidomide
- Letrozole
- Leucovorin
- Leuprolide
- Levalbuterol
- Levetiracetam
- Levocabastine
- Levocarnitine
- Levodopa and Carbidopa
- Levodopa, Carbidopa, and Entacapone
- Levofloxacin
- Levonorgestrel
- Levorphanol
- Levothyroxine
- Licorice
- Lidocaine
- Lidocaine and Epinephrine
- Lidocaine and Hydrocortisone
- Lindane
- Linezolid
- Liothyronine
- Liotrix
- Lisinopril
- Lisinopril and Hydrochlorothiazide
- Lithium
- Lomefloxacin
- Lomustine
- Loperamide
- Lopinavir and Ritonavir
- Loracarbef
- Loratadine
- Loratadine and Pseudoephedrine
- Lorazepam
- Losartan
- Losartan and Hydrochlorothiazide
- Loteprednol
- Loteprednol and Tobramycin
- Lovastatin
- Loxapine
- Lubiprostone
- Lutropin Alfa


