Sertraline



Zoloft®







Sertraline

(SER tra leen)

U.S. Brand Names
Zoloft®
Canadian Brand Names
Apo-Sertraline®; Gen-Sertraline; GMD-Sertraline; Novo-Sertraline; Nu-Sertraline; PMS-Sertraline; ratio-Sertraline; Rhoxal-sertraline; Sandoz-Sertraline; Zoloft®
Pharmacologic Category
Antidepressant, Selective Serotonin Reuptake Inhibitor
What key warnings should I know about before taking this medicine?
  • The desire to harm yourself is a serious symptom of depression. It may last until your depression is completely treated. If you are planning on harming yourself, dial 911 right away.
  • Please read the medication guide given to you.
Reasons not to take this medicine
  • All forms:
  • If you have an allergy to sertraline or any other part of this medicine.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
  • If you have taken isocarboxazid, phenelzine, or tranylcypromine in the last 14 days. Monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine) must be stopped 14 days before this medicine is started. Taking the two together could cause dangerously high blood pressure.
  • If you are taking pimozide.
  • Zoloft® Liquid:
  • If you are taking disulfiram.
  • If you have a latex allergy. Dropper contains rubber.
What is this medicine used for?
  • This medicine is used to treat anxiety.
  • This medicine is used to treat depression.
  • This medicine is used to treat eating disorders.
  • This medicine is used to treat impulse control disorder.
  • This medicine is used to treat obsessive-compulsive disorder.
  • This medicine is used to treat panic attacks.
  • This medicine is used to treat post-traumatic stress disorder.
  • This medicine is used to treat premenstrual mood disorder.
How does it work?
  • Sertraline increases chemicals in the brain.
  • In depression, sleep and appetite may improve quickly. Other depressive symptoms may take up to 4-6 weeks to improve.
How is it best taken?
  • To gain the most benefit, do not miss doses.
  • Take this medicine with or without food, but be consistent. Always take with food or always take on an empty stomach.
  • Mix liquid with cup of water, ginger ale, lemon-lime soda, lemonade, or orange juice.
  • Take this medicine in the morning.
What do I do if I miss a dose? (does not apply to patients in the hospital)
  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
  • Do not take a double dose or extra doses.
What are the precautions when taking this medicine?
  • If you have been taking this medicine for several weeks, talk with healthcare provider before stopping. You may want to gradually withdraw this medicine.
  • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
  • Avoid grapefruit and grapefruit juice.
  • Avoid alcohol (includes wine, beer, and liquor) or other medicines and natural products that slow your actions and reactions. These include sedatives, tranquilizers, mood stabilizers, antihistamines, and other pain medicine.
  • You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.
  • You can get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen; wear protective clothing and eyewear.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.
What are some possible side effects of this medicine?
  • Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.
  • Nervous and excitable.
  • Headache.
  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
  • Diarrhea.
  • Dry mouth.
  • Change in sexual ability or desire. This is usually reversible.
  • Inability to sleep.
What should I monitor?
  • Change in condition being treated. Is it better, worse, or about the same?
  • Dry mouth may cause an increase in cavities. Take good care of your teeth. See a dentist regularly.
  • Follow up with healthcare provider.
Reasons to call healthcare provider immediately
  • If you suspect an overdose, call your local poison control center immediately or dial 911.
  • Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
  • Very nervous and excitable.
  • No improvement in condition or feeling worse.
How should I store this medicine?
  • Store at room temperature.
  • Protect tablets from moisture. Do not store in a bathroom or kitchen.
General statements
  • If you have a life-threatening allergy, wear allergy identification at all times.
  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
Brand Names: